Steffen-Sebastian Bolz
Co-Founder, Executive Board Member & Chief Scientific Officer Aphaia Pharma
Seminars
Wednesday 1st October 2025
Panel Discussion: Expanding the Obesity Drug Development Pipeline from Peripheral Targets to Holistic Metabolic Health
11:00 am
- Exploring beyond traditional targets to understand how peripheral pathways and novel mechanisms address unmet needs in obesity care
- Integrating multi organ approached from gut-brain signalling with systemic metabolic health for synergistic efficacy to address payer demands, and drive adherence and market access
- Translating preclinical insights into clinically viable non-incretin therapies to diversify obesity drugs and move from placebo to active comparator trials
Wednesday 1st October 2025
Beyond Rapid Weight Loss: Harnessing Gut-Brain Signalling for Sustainable Metabolic Health
9:30 am
- Targeting sugar stimulation to reactivate nutrient-sensing cells to restore natural hormonal signalling and neural communication in the brain
- Focusing on rejuvenation to avoid aggressive weight loss and rebound effects for improved long-term adherence
- Promoting microvascular and multi-organ benefits by restoring systemic balance for better alignment with payer demands for cardio-metabolic endpoints
