Exploring Novel Multi-Targeted Approaches to Preserve Lean Mass & Enhance Metabolic Health in Obesity Therapy
- Reviewing the mechanistic rationale for multi-targeted therapies to achieve synergistic targeting of appetite suppression and muscle catabolism
- Comparing the analysis of body composition outcomes in recent trials to highlight trade-offs between fat loss efficacy, lean mass preservation, and tolerability
- Understanding the lessons from Phase 2 trials of multi-targeted obesity therapies to reveal practical challenges in dosing, patient adherence, and biomarker selection for body composition endpoints