New Insights into Regulation of Energy Metabolism by GIPR Agonism & Antagonism

  • Exploring the preclinical delineation of the effects GIP agonism vs. antagonism on food intake and metabolism
  • Discovering mechanisms of GLP-1/GIP dual agonism in the brain to accelerate the design of triple-agonists with improved tolerability
  • Proposing patient stratification strategies for GIP-targeted therapies to address heterogeneity in response, mitigating trial risks and expanding treatable populations